《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (11): 1029-1031.

• 综述 • 上一篇    下一篇

脑性瘫痪的病因学研究进展

李玉堂   

  1. 青岛市儿童医院神经康复科,山东青岛市 266011
  • 收稿日期:2009-10-09 出版日期:2009-11-01 发布日期:2009-11-01

Advance in Etiology of Cerebral Palsy (review)

LI Yu-tang   

  1. Neurological Rehabilitation Department, Qingdao Children's Hospital, Qingdao 266011, Shandong, China
  • Received:2009-10-09 Published:2009-11-01 Online:2009-11-01

摘要: 脑性瘫痪的病因包括产前、产时和产后。国内学者一般认为,产时和产后的因素是脑瘫的主要原因,而近年来国外学者根据流行病学、生化检测、动物实验、影像学等研究认为,产前因素占脑瘫病因的大多数,并提出了界定产前或产后因素的客观指标。本文综述了脑瘫的主要病因,并介绍脑瘫病因学路径(etiological pathway)理论,以及脑瘫患儿脑损伤时期的确定等。

关键词: 脑性瘫痪, 病因学, 早产儿, 宫内感染, 脑室周围白质软化, 病因学路径, 综述

Abstract: The causes of cerebral palsy are multifactorial, including antenatal, intrapartum and postnatal. Domestic scholars generally believed that intrapartum and postnatal factors are the main reasons for cerebral palsy, while in recent years, the foreign scholars suggest that prenatal factors account for the majority of the causes of cerebral palsy. This paper is to review the recent research on the causes of cerebral palsy and to introduce the theory of etiological pathway and determine the period of brain injury in cerebral palsy patients.

Key words: cerebral palsy, etiology, premature infant, intrauterine infection, periventricular leukomalacia (PVL), etiological pathway, review