《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (10): 905-907.

• 专题 • 上一篇    下一篇

创伤性脑损伤动物模型的研究进展

王娜;李林   

  1. 首都医科大学宣武医院药物研究室, 教育部神经变性病重点实验室, 北京市 100053
  • 收稿日期:2009-06-08 出版日期:2009-10-01 发布日期:2009-10-01

Advance in Animal Models of Traumatic Brain Injury (review)

WANG Na,LI Lin   

  1. The Department of Pharmacology, Xuanwu Hospital of Capital Medical University, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Beijing 100053, China
  • Received:2009-06-08 Published:2009-10-01 Online:2009-10-01

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摘要： 建立良好的创伤性脑损伤动物模型对其机制研究和治疗研究具有十分重要的意义。本文对几种主要的创伤性脑损伤动物模型的进展、制备方法、应用范围、各模型的特点和不足之处进行分析总结，并提出复制理想动物模型的几点标准。

关键词: 脑损伤, 创伤, 动物模型, 综述

Abstract: Good animal models of traumatic brain injury have a great significance in the pathogenesis research and treatment study. This paper reveiwed development in animal models of traumatic brain injury, including preparation Methods , application range, characteristics and shortcomings of each model.

Key words: brain injury, trauma, animal model, review