《中国康复理论与实践》

《中国康复理论与实践》 ›› 2009, Vol. 15 ›› Issue (09): 852-854.

• 临床研究 • 上一篇    下一篇

老年卒中相关性下呼吸道感染病原学及耐药性分析

陈军1a;刘长德1b   

  1. 1.清华大学玉泉医院，a.内科;b.检验科，北京市 100049
  • 收稿日期:2009-07-17 出版日期:2009-09-01 发布日期:2009-09-01

Pathogens and Resistance of Stroke-associated Lower Respiratory Tract Infection in Elderly Patients

CHEN Jun,LIU Chang-de   

  1. Department of Inter-medicine, Yuquan Hospital of Tsinghua University, Beijing 100049, China
  • Received:2009-07-17 Published:2009-09-01 Online:2009-09-01

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摘要： 目的 调查老年脑卒中患者卒中相关性下呼吸道感染病原学特点及耐药性。方法 对并发卒中相关性下呼吸道感染的住院患者痰菌培养阳性标本进行回顾性分析。结果 老年卒中相关性下呼吸道感染病原菌中革兰氏阴性杆菌占79.7%，依次为大肠埃希菌、铜绿假单胞菌、木糖氧化产碱杆菌、克雷伯菌属、鲍氏不动杆菌、嗜麦芽窄食单胞菌，革兰氏阳性菌占17.2%，真菌占3.1%；革兰氏阴性杆菌对亚胺培南、头孢他啶、阿米卡星较敏感，革兰氏阳性菌对去甲万古霉素敏感率均为100%。结论 老年卒中相关性下呼吸道感染病原菌主要为革兰氏阴性杆菌，以条件致病菌为主，对抗菌药物产生了不同程度的耐药。

关键词: 老年, 脑卒中, 卒中相关性下呼吸道感染, 病原菌, 抗药性

Abstract: Objective To investigate the pathogens and resistance of stroke-associated lower respiratory tract infection in elderly patients. Methods All the clinical isolates from sputum were analyzed retrospectively. Results There were 51 (79.7%) strains of Gram-negative bacilli, 11 (17.2%) strains of Gram-positive bacteria and 2 (3.1%) strains of fungi. The most important Gram-negative pathogens were Escherichia coli, Pseudomonas aeruginosa, Alcaligenes, Klebsiella, Acinetobacter baumanii, Stenotrophomonas maltophilia. Strains of Gram-negative bacteria were susceptible to imipenem, ceftazidime and amikacin, all strains of Gram-positive pathogens were susceptible to norvancomycin. Conclusion Gram-negative bacilli are the major pathogens in stroke-associated lower respiratory tract infection in elderly patients and the dominant is conditional pathogen.

Key words: elder, stroke, stroke-associated lower respiratory tract infection, pathogen, drug resistance