《中国康复理论与实践》

《中国康复理论与实践》 ›› 2011, Vol. 17 ›› Issue (8): 758-760.

• 论文 • 上一篇    下一篇

脊髓损伤并发尿路感染的菌群分布及药物治疗

卢守四，高钧   

  1. 中国康复研究中心北京博爱医院药剂科，北京市 100068。
  • 收稿日期:2011-03-24 修回日期:2011-06-08 出版日期:2011-08-25 发布日期:2011-08-25
  • 通讯作者: 肖树芹

Flora Distribution and Medication of Urinary Tract Infection in Spinal Cord Injury

LU Shou-si, GAO Jun.   

  1. Beijing Charity Hospital,China Rehabilitation Research center, Beijing 100068, China
  • Received:2011-03-24 Revised:2011-06-08 Published:2011-08-25 Online:2011-08-25

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摘要： 目的分析脊髓损伤后诱发尿路感染常见的致病菌，并提供有针对性的药物。方法回顾性分析2009 年1 月~2010 年10 月中国康复研究中心住院的240 例脊髓损伤并发泌尿系感染患者的细菌培养和抗生素药敏试验资料。结果泌尿系感染常见的致病菌前3 位以大肠埃希菌、肠球菌属、肺炎克雷伯菌等革兰氏阴性菌为主，部分伴有革兰氏阳性菌及真菌感染等。结论临床选用抗菌药物，应以细菌培养和药敏试验为依据，合理使用抗菌药物，防止频繁更换品种和连续长期使用抗菌药物，减少抗生素耐药。

关键词: 脊髓损伤, 尿路感染, 菌群, 药物治疗

Abstract: Objective To explore the common pathogenic bacteria and medication in urinary tract infection in the patients with spinal cord injury (SCI). Methods 240 SCI patients were analyzed retrospectively in China Rehabilitation Research Center from January 2009 to October 2010, who were diagnosed as urinary tract infection (UTIs) according to urine culture and bacterial identification. Results The first 3 positions of pathogenic bacteria were Gram-negative bacteria, such as Escherichia coli (53.8%), Enterococcus (8.9%), and Klebsiella pneumonia (8%), while some patients were followed Gram-positive bacteria and fungal infections. Conclusion The clinically selected antibacterial drugs should be based on the bacterial culture and drug susceptibility test to promote the antibacterial drugs use rationally, frequently changing the medicine and continuing the administration of antibacterial drugs for a long period of time should be avoided.

Key words: spinal cord injury, urinary tract infection, flora, medication