《中国康复理论与实践》

《中国康复理论与实践》 ›› 2004, Vol. 10 ›› Issue (03): 139-140.

• 专题 • 上一篇    下一篇

画钟试验和MMSE对阿尔茨海默病筛查的临床意义

于荣焕1,2;王荫华1   

  1. 北京大学第一医院神经内科 北京市 100034;开封市第一人民医院神经内科 河南开封市 475000
  • 收稿日期:2004-02-13 出版日期:2004-03-25 发布日期:2004-03-25

Clinical significance of clock-drawing test and MMSE in Alzheimer's disease

YU Rong-huan, WANG Yin-hua   

  1. Department of Neurology, First Hospital,Peking University, Beijing 100034,China
  • Received:2004-02-13 Published:2004-03-25 Online:2004-03-25

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摘要： 目的探讨画钟试验(CDT)和简易精神状态检查量表(MMSE)对阿尔茨海默病(AD)测查的临床意义,为AD的早期筛查选择简单易行的测查工具提供依据。方法采用MMSE和CDT对AD组及健康对照组进行智能测查。结果AD患者在定向力、即刻记忆、计算力、短时记忆、语言能力得分明显降低,两组各亚项和MMSE总分对比均有显著性差异(P<0.05);不同程度的AD患者MMSE各亚项与对照组比,轻度AD在定向力、即刻记忆、计算力、短时记忆、语言能力得分明显降低,重度AD患者在各亚项得分降低更明显,差异明显(P<0.01),按MMSE不同分度的轻、中、重度AD患者CDT得分与对照组比较明显降低,有非常显著性差异(P<0.01)。结论CDT和MMSE等认知工具不仅适合于临床对早期痴呆患者的筛查,还可以帮助判断痴呆的严重程度。

关键词: 阿尔茨海默病(AD), 画钟试验(CDT), 简易精神状态检查量表(MMSE), 痴呆

Abstract: ObjectiveTo observe the clinical sense of clock-drawing test(CDT) and Mini Mental Status Examination(MMSE) in Alzheimer's disease(AD). MethodsMMSE and CDT were used to assess the intellectual ability in AD group and control group. ResultsThe orientation force, immediate memory, ability of calculation, short-term memory and speech ability in AD group were significantly decreased than that of the control group(P<0.05). The score of CDT in AD group was markedly suppression than that of control group(P<0.01). ConclusionThe CDT and MMSE are the ideal cognitive screening test to determine the degree in Alzheimer's disease.

Key words: Alzheimer's disease(AD), clock-drawing test(CDT), Mini Mental Status Examination(MMSE)