《中国康复理论与实践》

《中国康复理论与实践》 ›› 2003, Vol. 9 ›› Issue (11): 658-659.

• 临床康复 • 上一篇    下一篇

早产与小儿脑性瘫痪的关系

郭先鸣; 王勇; 梁友玲; 杨广林   

  1. 广西妇幼保健院 广西南宁市 530003
  • 收稿日期:2003-09-03 出版日期:2003-11-25 发布日期:2003-11-25

Relation between premature delivery and cerebral palsy

GUO Xian-ming, WANG Yong, LIANG You-ling, et al   

  1. Guangxi Women & Children Health Hospital, Guangxi Children’s Hospital, Nanning 530003, Guangxi,China
  • Received:2003-09-03 Published:2003-11-25 Online:2003-11-25

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摘要： 目的探讨早产儿与小儿脑性瘫痪(CP)的关系。方法1998年5月-12月在南宁市、横县、钦州市钦北区(原钦州县)进行以乡(镇)为单位群体抽样调查,对抽样乡(镇)全部1-6岁儿童进行CP患病状况调查。由经过统一培训合格的儿科医生参加工作。结果共调查1-6岁小儿150806例,确诊CP患儿193例,患病率128‰;早产儿872例,确诊CP46例,患病率52.75‰;足月儿149934例,发生CP142例,患病率0.95‰(P<0.001)。胎龄越小,CP患病率越高。46例早产儿CP中,其母既往有异常孕产史18人(26人次),占39.1%;有妊娠合并症36人(占78.3%);新生儿期患病23人(30人次),占50%。结论早产是与脑瘫高度关联的危险因素。

关键词: 早产儿, 脑性瘫痪, 患病率, 流行病学调查

Abstract: ObjectiveTo study the relation between premature and cerebral palsy(CP).MethodsTo sample all the children between the age of 1 to 6 years old for investigating CP situation in Nanning city, Heng county and Qinbei region of Qinzhou city (once named Qinzhou county ) from May to December, 1998 by qualified pediatricians.ResultsThe total investigating cases were 150,806,in which diagnosed CP were 193 cases and the incidence of CP was 1.28‰. Among them, premature infants were 872 and diagnosed CP were 46,the incidence of CP was 52.75‰ in this group. While term laboring infants were 149,934 with CP 142 and the incidence of CP was 0.95‰. The difference between two groups was very significant(P<0.001).The shorter the gestational weeks were, the higher the incidence of the CP was. Among 46 premature infants with CP, there were 18 cases' mothers(26 person times) involved in abnormal pregnancy and delivery history, accounted for 39.1%, while 36 with pregnancy complications(78.3%). There were 23 cases (30 person times) suffered from the disease during neonate, accounted for 50%.ConclusionThe premature delivery is a risk factor associated with childhood CP.

Key words: premature infant, cerebral palsy, incidence, epidemiologic data