《中国康复理论与实践》

《中国康复理论与实践》 ›› 2003, Vol. 9 ›› Issue (07): 412-413.

• 基础研究 • 上一篇    下一篇

刺激间隔对兔痛觉诱发电位的影响

卢惠苹;吴宗耀   

  1. 第三军医大学附属西南医院康复理疗科 重庆市 400038
  • 收稿日期:2003-02-01 出版日期:2003-07-25 发布日期:2003-07-25

Effects of inter-stimulus interval on pain evoked potential in rabbits

LU Hui-ping,WU Zong-yao   

  1. Department of Physical Medicine and Rehabilitation,Southwest Hospital,the 3ed Military Medical University,Chongqing 400038,China
  • Received:2003-02-01 Published:2003-07-25 Online:2003-07-25

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摘要： 目的对家兔进行痛刺激间隔与诱发的事件相关电位关系的研究,探讨痛刺激间隔对诱发电位的影响,筛选兔痛觉诱发电位最优的刺激间隔。方法在家兔颅骨内F4点安放电极,用不同的刺激间隔按痛觉Oddball刺激序列记录该部位的波形并对其进行分析。结果痛觉P2、N2、P3a的潜伏期各刺激间隔间无显著性差异(P>0.5),波幅在刺激间隔为8秒时最高(P<0.05),分别为(63.33±25.93)μv、(62.25±13.86)μv、(56.17±9.82)μv。 结论兔痛觉诱发电位有一最佳刺激间隔。

关键词: 刺激频率, 诱发电位, 痛觉, 兔

Abstract: ObjectiveTo study the effects of painful inter-stimulus interval on event-related potentials in rabbits for best inter-stimulus interval.MethodsElectrode was attached to F4 site on rabbits' skull. An Oddball paradigm stimulus were adopted. The waveforms recorded under different inter-stimulus interval were analysed.ResultsThe latency of pain evoked potentials P2,N2,P3a under different inter-stimulus interval showed no significant difference.The amplitude was highest when the interval was 8s.ConclusionsThere is a best inter-stimulus interval for pain evoked potential.

Key words: inter-stimulus interval, evoked potentials, pain, rabbits