《中国康复理论与实践》

《中国康复理论与实践》 ›› 2003, Vol. 9 ›› Issue (06): 326-327.

• 神经康复 • 上一篇    下一篇

头颅局部亚低温治疗急性进展性脑梗死临床研究

朱士文1; 任庆华2; 李义召1; 宋成忠1; 孙远标1   

  1. 1.济南长城医院神经内科 山东济南市 250100;2.费县人民医院内科 山东费县 273400
  • 收稿日期:2002-10-14 出版日期:2003-06-25 发布日期:2003-06-25

Observation of effects of the brain-located mild hypothermia therapy on acute progressive cerebral infarction

ZHU Shi-wen,REN Qing-hua,LI Yi-zhao,et al   

  1. Department of Neurology,Jinan Great Wall Hospital,Jinan 250100,Shandong,China
  • Received:2002-10-14 Published:2003-06-25 Online:2003-06-25

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被引次数

27

摘要： 目的探讨头颅局部亚低温治疗急性进展性脑梗死的临床疗效。方法将60例急性进展性脑梗死患者随机分为观察组(30例)和对照组(30例)。观察组在药物治疗基础上加用亚低温治疗,对照组为单纯药物综合治疗。72h和7d后对两组患者进行脑梗死体积及瘫痪肢体神经功能缺损评定。结果治疗72h、7d后,观察组患者的脑梗死体积明显小于对照组(P<0.01),两组患者的瘫痪肢体神经功能评分有高度显著性差异(P<0.01)。结论头颅局部亚低温治疗可以减轻急性进展性脑梗死患者的脑水肿,有脑保护作用,为应用低温治疗脑梗死提供了重要的理论依据。

关键词: 局部亚低温, 急性进展性脑梗死, 治疗

Abstract: ObjectiveTo study effects of treating acute progressive cerebral infarction by the brain-located mild hypothermia therapy.Methods60 patients were randomly divided into the treatment group (30 cases) and the control group (30 cases). Drugs were used in both groups, and the located mild hypothermia therapy was only applied in the treatment group. After 72 hours and 7 days, the volume of cerebral infarction and the nerve function deficiency (NFD) scores of hemiplegic limbs were compared.ResultsThe volume of cerebral infarction of the treatment group was significantly smaller than that of the control group (P<0.01).There were significant differences on the neurological impairment scores between two groups (P<0.01).Conclusions The brain-located mild hypothermia therapy can reduce hydrocephalus of patients with acute progressive cerebral infarction, and have brain protection. These results provide an important theoretical foundation for the treatment of cerebral infraction with low-temperature therapy.

Key words: located mild hypothermia, acute progressive cerebral infarction, treatment