《中国康复理论与实践》 ›› 2003, Vol. 9 ›› Issue (06): 324-325.

• 神经康复 • 上一篇    下一篇

加兰他敏对脑梗死患者运动功能的影响

张秀娟   

  1. 邢台市人民医院 河北邢台市 054031
  • 收稿日期:2003-03-21 出版日期:2003-06-25 发布日期:2003-06-25

Effect of galanthamine on motor function of patients with cerebral infarction

ZHANG Xiu-juan   

  1. Department of Rehabilitation,Xingtai People's Hospital,Xingtai 054031,Hebei,China
  • Received:2003-03-21 Published:2003-06-25 Online:2003-06-25

摘要: 目的探讨加兰他敏 (galanthamine)对脑梗死患者运动功能的影响。方法将78例脑梗死患者随机分为加兰他敏治疗组(40例)和对照组(38例)。对照组给予神经内科常规治疗和康复治疗,加兰他敏组在此基础上加用氢溴酸加兰他敏(galan-thamine hydrobromide)治疗。于治疗前及治疗6周后采用简式Fugl-Meyer运动量表评定患者运动功能。结果两组患者治疗后的运动功能评分均较治疗前有提高(P<0.05—0.01),但治疗组的运动功能评分明显高于对照组(P<0.01)。结论氢溴酸加兰他敏能够提高脑梗死患者的运动功能和康复治疗的疗效。

关键词: 加兰他敏, 脑梗死, 康复评定, 运动功能

Abstract: ObjectiveTo explore the effect of galanthamine on motor function of patients with cerebral infarction.Methods78 patients were randomly divided into the galanthamine treatment group (40 cases) and the control group (38 cases). Patients in the control group were given clinical routine treatment and rehabilitation training, while the galanthamine treatment group took galanthamine orally in addition. Evaluations were done in pre-treatment and post 6 weeks. Motor function was assessed with Fugl-Meyer motor scale (FMMS).ResultsThe increase of FMMS scores in each group had a significant difference ( P<0.05-0.01), while the process of scores in the galanthamine treatment group was superior to that in the control group (P<0.01).Conclusions Galanthamine hydrobromide is an effect drug on improving activities of motor function and ameliorating the therapeutic efficacy of rehabilitation to patients with cerebral infarction.

Key words: galanthamine, cerebral infarction, rehabilitation assessment, motor function