《中国康复理论与实践》 ›› 2015, Vol. 21 ›› Issue (10): 1178-1181.

• 基础研究 • 上一篇    下一篇

胆红素抗氧化系统与缺血性脑卒中的关系

田婷,石正洪   

  1. 兰州大学第二医院神经内科临床医学中心,甘肃兰州市 730000。
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-10-25 发布日期:2015-10-25

Relationship between Antioxidant System of Bilirubin and Ischemic Stroke (review)

TIAN Ting, SHI Zheng-hong   

  1. Clinical Medicine Center of Neurology Department, Second Hospital, Lanzhou University, Lanzhou, Gansu 730000, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-10-25 Online:2015-10-25

摘要: 胆红素是衰老红细胞破坏降解的终产物。近年来的研究发现它是内源性抗氧化剂,具有抗动脉粥样硬化、清除自由基、保护机体组织器官的作用。其与缺血性脑卒中相关性的研究越来越多,本文就目前已知的胆红素抗氧化系统与动脉粥样硬化及缺血性脑卒中的发生、发展及预后之间的关系进行综述。

关键词: 缺血性脑卒中, 胆红素, 抗氧化剂, 动脉粥样硬化, 综述

Abstract: Bilirubin is the final product of aging red blood cells when they were destroyed and degraded. Recent studies have demonstrated that it is a kind of endogenous antioxidant, which plays an important role in anti-atherosclerosis, scavenging free radicals and protecting the tissues and organs from damage. More and more studies have focused on the correlation between bilirubin and ischemic stroke. This article summarized the relationship between the antioxidant system of bilirubin and the occurrence, development and prognosis of atherosclerosis and ischemic stroke.

Key words: ischemic stroke, bilirubin, antioxidant, atherosclerosis, review