《中国康复理论与实践》

《中国康复理论与实践》 ›› 2014, Vol. 20 ›› Issue (7): 675-678.

• 论文 • 上一篇    下一篇

超低频经颅磁刺激对脑性瘫痪患儿脑血流的影响

谭祥芹，吴卫红，曾凡勇，李雪梅，席冰玉   

  1. 1.首都医科大学康复医学院，北京市100068；2.中国康复研究中心北京博爱医院，a.儿童康复科；b.功能检查科，北京市100068。
  • 收稿日期:2013-10-22 修回日期:2014-01-26 出版日期:2014-07-25 发布日期:2014-07-25
  • 通讯作者: 吴卫红

Effect of Ultra-low Frequency Transcranial Magnetic Stimulation on Cerebral Blood Flow in Children with Cerebral Palsy

TAN Xiang-qin, WU Wei-hong, ZENG Fan-yong, et al.   

  1. Capital Medical University School of Rehabilitation Medicine, Department of Children Rehabilitation,Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing 100068, China
  • Received:2013-10-22 Revised:2014-01-26 Published:2014-07-25 Online:2014-07-25

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摘要： 目的观察超低频经颅磁刺激对脑瘫痉挛型双瘫患儿脑血流动力学的影响。方法将36 例脑瘫痉挛型双瘫患儿分为对照组(n=21)和观察组(n=15)，另19 名正常儿童为正常组。在基础康复治疗的同时，观察组患儿进行超低频经颅磁刺激治疗，于治疗前后应用经颅彩色多普勒超声(TCD)对所有患儿以及正常儿童的脑血流动力学参数进行检测。结果治疗前，观察组数条动脉的流速低于正常组，搏动指数及阻力指数高于正常组(P<0.05)；治疗后，观察组较对照组的数条动脉流速有不同程度的提高，搏动指数及阻力指数有不同程度的降低(P<0.05)。结论脑瘫痉挛型双瘫儿童的脑内血流呈低流速高阻力的状况，而超低频经颅磁刺激可以改善其血流状况。

关键词: 脑性瘫痪, 超低频经颅磁刺激, 脑血流, 经颅彩色多普勒

Abstract: Objective To observe the effect of ultra-low frequency transcranial magnetic stimulation on cerebral blood flow in children with spastic diplegia cerebral palsy. Methods 36 cases of spastic diplegia cerebral palsy were divided into control group (n=21) and obsevation group (n=15), 19 healthy children were as normal group. The control group received conventional rehabilitation training. The obsevation group received the ultra-low frequency transcranial magnetic stimulation in addition. All the children received the check of transcranial color Doppler (TCD). Results Several arterials flow velocity was lower, several arterials pulsatility index and resistance index were higher in the obsevation group than in the normal group before treatment (P<0.05). Compared with the control group, the arterial flow of obsevation group improved, pulsatility index and resistance index decreased in some degrees in the obsevation group after treatment (P<0.05). Conclusion The cerebral blood flow is of low velocity and high resistance in spastic diplegia children, while ultra-low frequency magnetic stimulation could improve the condition of cerebral flow.

Key words: cerebral palsy, ultra-low frequency transcranial magnetic stimulation, cerebral blood flow, transcranial color Doppler