《中国康复理论与实践》

《中国康复理论与实践》 ›› 2014, Vol. 20 ›› Issue (7): 626-628.

• 论文 • 上一篇    下一篇

后肢制动对大鼠比目鱼肌神经传导功能的影响

赵雪红，高艳，樊小力，唐一通   

  1. 1.湖北文理学院医学院机能学部，湖北襄阳市441053；2. 西安交通大学医学院生理教研室，陕西西安市710061。
  • 收稿日期:2014-02-25 修回日期:2014-03-31 出版日期:2014-07-25 发布日期:2014-07-25
  • 通讯作者: 樊小力

Alterations in Soleus Nerve Conduction Velocities Induced by Hindlimb Immobilization in Rats

ZHAO Xue-hong, GAO Yan, FAN Xiao-li, et al.   

  1. Medical Function Department, Medical College of Hubei University of Arts and Science, Xiangyang, Hubei 441053, China
  • Received:2014-02-25 Revised:2014-03-31 Published:2014-07-25 Online:2014-07-25

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被引次数

1

摘要： 目的观察后肢制动对大鼠比目鱼肌神经传导功能的影响。方法24 只健康雌性Sprague-Dawley 大鼠随机分为正常对照组、制动7 d 组和制动14 d 组，每组8 只。采用石膏固定建立后肢制动模型，用电生理技术记录背根细束的传导速度和M波潜伏期。结果与正常对照组比较，制动7 d 后，大鼠比目鱼肌肌梭Ⅰ类传入神经纤维的传导速度减慢(P<0.05)；制动14 d 后，M波潜伏期延长(P<0.05)。结论制动条件下神经传导功能降低，而且传入神经纤维的功能改变要早于、重于运动神经纤维。

关键词: 制动, 骨骼肌, 传导速度, 大鼠

Abstract: Objective To observe the alterations in soleus nerve conduction velocities induced by hindlimb immobilization. Methods 24 healthy Sprague-Dawley rats were randomly divided into control group, immobilization 7 days group and immobilization 14 days group with 8 cases in each group. The plaster cast was fixed as the method to induce a hindllimb immobilization model in rats. The afferent thin fibers conduction velocity and the latency of M wave were observed with electrophysiological technique. Results 7 days after immobilization,the conduction velocity of muscle spindle primary afferent fiber decreased (P<0.05), the latency of M wave significantly prolonged 14 days after immobilization (P<0.05). Conclusion The soleus nerve conduction velocities decrease significantly following hindlimb immobilization and the alterations in afferent fibers are more serious than that in efferent fibers.

Key words: immobilization, skeletal muscle, conduction velocity, rats