《中国康复理论与实践》

《中国康复理论与实践》 ›› 2014, Vol. 20 ›› Issue (4): 389-391.

• 论文 • 上一篇    下一篇

巨脑回畸形与脑室周围白质软化症所致脑性瘫痪的临床分析

袁俊英，曾宪旭，王遐   

  1. 郑州大学第三附属医院儿童康复科，河南郑州市450052。
  • 收稿日期:2013-05-30 修回日期:2013-12-04 出版日期:2014-04-25 发布日期:2014-04-25

Clinical Features of Cerebral Palsy after Pachygyria and Periventricular Leukomalacia

YUAN Jun-ying, ZENG Xian-xu, WANG Xia.   

  1. Department of Children Rehabilitation Medicine, the Third Hospital of Zhengzhou University, Zhengzhou 450052, Henan, China
  • Received:2013-05-30 Revised:2013-12-04 Published:2014-04-25 Online:2014-04-25

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摘要： 目的探讨巨脑回畸形与脑室周围白质软化症(PVL)导致的脑瘫临床表现、预后等方面的区别与联系。方法回顾性研究巨脑回所致脑瘫15 例和PVL所致脑瘫35 例，比较种不同原因所致脑瘫在确诊年龄、分型、并发症、粗大运动功能分级(GMFCS)等方面的不同。结果巨脑回畸形组所致脑瘫患儿确诊年龄要显著早于PVL组(P<0.001)，GMFCS分级低于PVL组(P<0.05)，癫痫发生率高于PVL组(P<0.05)，智力显著低于PVL组(P<0.001)。结论巨脑回畸形所致脑瘫整体发育比PVL发育要差，其预后也相对较差。

关键词: 脑性瘫痪, 巨脑回畸形, 脑室周围白质软化症

Abstract: Objective To compare the features of cerebral palsy with pachygyria or periventricular leukomalacia (PVL). Methods 15 children with pachygyria and 35 children with PVL were included. Their diagnosed age, clinical subtype, complications, Gross Motor Function Classification System (GMFCS) were compared. Results The diagnosed age was significantly younger (P<0.001), the GMFCS was lower (P<0.05), the incidence rate of epilepsy was higher (P<0.05), and the intelligence was significantly lower (P<0.001) in the pachygyria group than in the PVL group. Conclusion Cerebral palsy children with pachygyria develope worse than that with PVL, as well as their prognosis.

Key words: cerebral palsy, pachygyria, periventricular leukomalacia