《中国康复理论与实践》

《中国康复理论与实践》 ›› 2013, Vol. 19 ›› Issue (09): 869-871.

• 论文 • 上一篇    下一篇

A型肉毒毒素矫正脑卒中后中枢性面瘫的疗效

杨远滨，张京，张静，肖娟   

  1. 1.首都医科大学宣武医院康复科，北京市100053；2.首都医科大学世纪坛医院神经内科，北京市100038；3.北京市丰台区西罗园社区卫生服务中心，北京市100077。
  • 收稿日期:2013-05-30 修回日期:2013-08-01 出版日期:2013-09-25 发布日期:2013-09-25

Effect of Botulinum Toxin-A Injection on Central Facial Palsy Post Stroke

YANG Yuan-bin, ZHANG Jing, ZHANG Jing, et al.   

  1. Department of Rehabilitaion, Xuanwu Hospital of Capital Medical University, Beijing 100053, China
  • Received:2013-05-30 Revised:2013-08-01 Published:2013-09-25 Online:2013-09-25

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摘要： 目的观察肉毒毒素健侧面肌注射矫正脑卒中后患者患侧中枢性面瘫的效果。方法30 例脑卒中后中枢性面瘫的患者分为治疗组和对照组。对照组给予面肌运动训练，治疗组在此基础上，依据病情选择健侧面肌进行A 型肉毒毒素注射。注射前、注射后4 周测定嘴角至门齿中缝的双侧距离差(D1)、眼骨性外眦到嘴角的双侧距离差(D2)。结果治疗后，治疗组静态、动态D1、D2 均较治疗前减小(P<0.05)，且较对照组减小(P<0.05)。结论A型肉毒毒素注射能进一步矫正中枢性面瘫。

关键词: 脑卒中, 中枢性面瘫, A型肉毒毒素, 康复

Abstract: Objective To explore the effect of Botulinum toxin-A (BTX-A) injected into the contralateral facial muscle on central facial palsy post stroke. Methods 30 stroke patients with moderate to severe central facial palsy were recruited (course of 3~10 months). They were divided into control group (n=15) and treatment group (n=15), who accepted facial training and BTX-A injection in addition, respectively.The bilateral deference of distance from angulus oris to the midline of the teeth(D1) and from the paropia to the angulus oris (D2) were measured before and 4 weeks after injection. Results The D1 and D2 both at resting and movement all decreased after injection in the treatment group, and decreased more than those in the control group. Conclusion BTX-A injection can further correct central facial palsy post stroke.

Key words: stroke, central facial palsy, Botulinum toxin-A, rehabilitation