《中国康复理论与实践》

《中国康复理论与实践》 ›› 2013, Vol. 19 ›› Issue (3): 223-226.

• 论文 • 上一篇    下一篇

椎基底动脉延长扩张症的CT灌注特征

罗沛霖，洪璇阳，周毅方，李龙，王海林

  

  1. 1.广州医学院附属武警广东总队医院放射科，广东广州市510507；2.广州医学院附属广州市第一人民医院放射科，广东广州市510180。
  • 收稿日期:2012-09-27 修回日期:2012-10-28 出版日期:2013-03-25 发布日期:2013-03-25
  • 通讯作者: 王海林

Features of CT Perfusion for Vertebrobasilar Dolichoectasia

LUO Pei-lin, HONG Xuan-yang, ZHOU Yi-fang, et al.   

  1. Department of Radiology,Guangdong Hospital, Chinese People's Armed Police Forces, Guangzhou 510507, Guangdong, China
  • Received:2012-09-27 Revised:2012-10-28 Published:2013-03-25 Online:2013-03-25

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摘要： 目的探讨椎基底动脉延长扩张症(VBD)患者动态CT 灌注成像方法的应用价值。方法2011 年2 月~2012 年3 月经临床及影像学检查确诊为VBD的患者13 例为观察组，同期22 例临床和CT 均提示无颅脑疾病者为正常对照组，记录年龄，进行动态CT 灌注成像，在双侧小脑半球、小脑脚及桥脑白质区对称各选取3 个感兴趣区，分别测量各组脑血流量(CBF)、脑血容量(CBV)、平均通过时间(MTT)和达峰时间(TTP)，以及观察组基底动脉的直径。结果两组桥脑、小脑脚和小脑白质的TTP 相比具有显著性差异(P<0.05)，而CBF、CBV 及MTT 无显著性差异(P>0.05)。观察组年龄和基底动脉直径与桥脑、小脑脚和小脑白质的CBF、CBV、MTT 及TTP 相比无显著性相关(P>0.05)。结论CT 灌注成像可以显示VBD后循环灌注的特异性，作为其血流动力学方面的辅助诊断。

关键词: 计算机断层X线成像, CT 灌注成像, 椎基底动脉延长扩张症

Abstract: Objective To evaluate the features of CT perfusion for vertebrobasilar dolichoectasia (VBD). Methods The image data of 13 cases with VBD as observation group and 22 cases of normal controls were retrospectively analyzed from February 2011 to March 2012. 3 regions of interest (ROI) in white matter of cerebellum, cerebellar peduncle and pons were drown symmetry to measure the parameters including cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT) and time to peak (TTP). The diameter of basilar artery and the age of the observation group were also measured. Results There was significant difference between 2 groups in TTP in all ROI (P<0.05), and no significant difference in CBF, CBV and MTT in all ROIs (P>0.05). The age, the diameter of basilar artery did not correlated with perfusion parameters (P>0.05) in the observation group. Conclusion CT perfusion imaging can demonstrate some features of posterior circulation as auxiliary diagnosis of VBD.

Key words: computed tomography, CT perfusion, vertebrobasilar dolichoectasia