《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (11): 1047-1048.

• 论文 • 上一篇    下一篇

诱导性多能干细胞在遗传性心脏病实验研究中的应用

周云国，曹玲玲，洪葵   

  1. 南昌大学第二附属医院心内科，江西省分子医学重点实验室，江西南昌市330006。
  • 收稿日期:2012-07-08 修回日期:1900-01-01 出版日期:2012-11-25 发布日期:2012-11-25
  • 通讯作者: 洪葵

Application of Induced Pluripotent Stem Cells in Experiment Study of Hereditary Heart Disease (review)

ZHOU Yun-guo, CAO Ling-ling, HONG Kui.   

  1. Cardiology Department, the Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Molecular Medicine, Nanchang 330006, Jiangxi, China
  • Received:2012-07-08 Revised:1900-01-01 Published:2012-11-25 Online:2012-11-25

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摘要： 人类诱导性多能干细胞(iPS 细胞)的建立是目前最重要的科技进展之一。近年来，iPS 细胞应用于遗传性心脏病细胞模型的建立，及其iPS 细胞治疗动物心梗模型成功，为探索遗传性心脏病的发病机制和治疗带来了光明前景。

关键词: 诱导性多能干细胞, 心肌细胞, 遗传性心脏病, 综述

Abstract: The establishment of induced pluripotent stem (iPS) cells is considered as one of the most important progresses in science and technology nowadays. In recent years, the iPS cells have been used in the construction of cellular model for hereditary heart disease, and the successful treatment in animal model of myocardial infarction, which brings a bright future for exploring the pathogenesis and therapy of hereditary heart disease.

Key words: induced pluripotent stem cells, cardiomyocytes, hereditary heart disease, review