《中国康复理论与实践》

《中国康复理论与实践》 ›› 2012, Vol. 18 ›› Issue (10): 916-918.

• 论文 • 上一篇    下一篇

A型肉毒毒素配合药浴对脑性瘫痪患儿痉挛的疗效

陈强，许惠强，金少枫，苏坤阳，黄泽华，邹少惠   

  1. 厦门市残联康复医院，福建厦门市361012
  • 收稿日期:2012-04-16 修回日期:2012-06-11 出版日期:2012-10-25 发布日期:2012-10-25
  • 通讯作者: 许惠强

Effect of Botulinum Toxin Type A and Medicated Bath on Spasm for Children with Cerebral Palsy

CHEN Qiang, XU Hui-qiang, JIN Shao-feng, et al   

  1. Xiamen FIMITIC Rehabilitation Hospital, Xiamen 361012, Fujian, China
  • Received:2012-04-16 Revised:2012-06-11 Published:2012-10-25 Online:2012-10-25

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摘要： 目的探讨A型肉毒毒素注射与康复训练和药浴相结合治疗脑瘫患儿痉挛的效果。方法80 例痉挛型和混合型脑瘫患儿分为两组，每组40 例。对照组采用运动疗法；观察组采用A型肉毒毒素注射后进行康复训练和药浴。治疗前后采用改良Ashworth评定量表(MAS)、粗大运动功能测试量表(GMFM-88)进行评定。结果治疗3 个月后，两组患儿MAS评分、GMFM评分均优于治疗前(P<0.05)，观察组疗效优于对照组(P<0.05)。结论A型肉毒毒素注射配合康复训练和药浴能降低肌张力，有效提高痉挛型和混合型脑瘫患儿的粗大运动功能。

关键词: 脑性瘫痪, 痉挛, A型肉毒毒素, 注射, 药浴, 康复, 粗大运动功能

Abstract: Objective To explore the effect of Botulinum toxin type A (BTX-A) injection combined with rehabilitation training and medicated bath on spasm for children with cerebral palsy. Methods 80 children with spastic and mixed cerebral palsy were randomly divided into two groups with 40 cases in each group. The control group received physical therapy, and the observation group received BTX-A injection and rehabilitation training and medicated bath. They were assessed with modified Ashworth scale (MAS) and Gross Motor Function Measure (GMFM-88) before and 3 months after treatment. Results The scores of MAS and GMFM were better in 2 groups after treatment (P<0.05) and the observation group was better than that of the control group (P<0.05). Conclusion BTX-A injection combined with medicated bath can reduce muscle tension, improve gross motor function of children with spastic and mixed cerebral palsy.

Key words: cerebral palsy, spasm, Botulinum toxin type A, injection, medicated bath, rehabilitation, gross motor function