《中国康复理论与实践》

《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (4): 356-358.

• 论文 • 上一篇    下一篇

妊娠期可逆性后部白质脑病综合征：附4例报道

吴士文1,2，郭军红3，张舒凤2，于生元1   

  1. 1.解放军总医院神经内科，北京市 100853；2.武警总医院神经内科，北京市 100039；3.山西医科大学第一医院神经内科，山西太原市 030001。
  • 收稿日期:2010-03-04 修回日期:1900-01-01 出版日期:2010-04-25 发布日期:2010-04-25
  • 通讯作者: 于生元

Reversible Posterior Leukoencephalopathy Syndrome during Gestation Period: 4 Cases Report

WU Shi-wen, GUO Jun-hong, ZHANG Shu-feng, et al.   

  1. Department of Neurology, The General Hospital of PLA, Beijing 100853, China
  • Received:2010-03-04 Revised:1900-01-01 Published:2010-04-25 Online:2010-04-25

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摘要： 目的探讨妊娠期可逆性后部白质脑病综合征的临床及影像学特征。方法回顾分析近3年收治的4例妊娠期可逆性后部白质脑病综合征患者的临床与影像学改变。结果4例患者主要表现为头痛、癫痫发作、意识障碍及视力障碍。典型的MRI检查表现为对称性的局灶部位的脑水肿，主要位于顶、枕叶以及额叶，多在数周内恢复。其中3例患者发生子痫，且均发生在产后的2 d内。结论妊娠期可逆性后部白质脑病综合征有其特征性临床特征，常存在于子痫者中。

关键词: 妊娠期, 可逆性后部白质脑病综合征

Abstract: ObjectiveTo explore the clinical and imageological features of reversible posterior leukoencephalopathy syndrome(RPLS) during gestation period.MethodsClinical and imageological data of 4 pregnant women with RPLS were analyzed retrospectively.ResultsHeadache, seizure, confusion and visual loss were the mainly clinical manifestations. At MR imaging, the brain typically demonstrated focal regions of symmetric hemispheric edema which may disappear in several weeks. The parietal and occipital lobes were most commonly affected, followed by the frontal lobe cerebral vasoconstriction syndrome. Three of the four patients suffered eclampsia which happened in two days after delivery.ConclusionThere are distinctively clinical features in posterior leukoencephalopathy syndrome during gestation period. Most of them are invovled in patients with eclampsia.

Key words: gestation period, reversible posterior leukoencephalopathy syndrome