《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (3): 221-223.

• 论文 • 上一篇    下一篇

脊髓损伤动物模型的建立及其评价

田伟1,2,张焱1,2,孙岚1,2,王征美1,2   

  1. 1.首都医科大学康复医学院,北京市 100068;2.中国康复研究中心北京博爱医院,北京市 100068。
  • 收稿日期:2010-01-15 修回日期:1900-01-01 出版日期:2010-03-25 发布日期:2010-03-25

Establishment and Evaluations of the Spinal Cord Injury Model (review)

TIAN Wei,ZHANG Yan,SUN Lan,et al.   

  1. Capital Medical University School of Rehabilitation Medicine, Beijing Charity Hospital, China Rehabilitation Research Centre, Beijing 100068, China
  • Received:2010-01-15 Revised:1900-01-01 Published:2010-03-25 Online:2010-03-25

摘要: 脊髓损伤是一种致残率很高的疾病,建立理想的脊髓损伤动物模型对于实验研究尤为重要。脊髓损伤和再生修复机制是目前神经科学研究中的难题,脊髓损伤动物模型的建立和研究进展为突破这一难题起到了非常重要的作用。本文旨在介绍建立脊髓损伤动物模型的动物选择,以及各种脊髓损伤模型的建立方法、特点,并对常用的脊髓损伤动物模型进行评价。

关键词: 脊髓损伤, 动物模型, 综述

Abstract: Spinal cord injury often resulted in disability. It is important to establish an ideal animal model to study spinal cord injury, its pathogenesis, regeneration and repair, etc. This article reviewed the establishment of models, including animals, method, characteristics, and discussed the frequently used models.

Key words: spinal cord injury, animal model, review