《中国康复理论与实践》

《中国康复理论与实践》 ›› 2010, Vol. 16 ›› Issue (2): 168-170.

• 论文 • 上一篇    下一篇

药物结合技能训练对恢复期精神分裂症患者康复的影响

段武钢，孙全新，曾德志，顾桂英，郑桂芝，吴芳   

  1. 咸宁学院附属第二医院，湖北咸宁市 437100。
  • 收稿日期:2009-12-04 修回日期:1900-01-01 出版日期:2010-02-25 发布日期:2010-02-25

Effect of Antipsychotics plus Skill Training on Schizophrenics at Recovery

DUAN Wu-gang, SUN Quan-xin, ZENG De-zhi, et al.   

  1. The Second Affiliated Hospital of Xianning University, Xianning 437100, Hubei, China
  • Received:2009-12-04 Revised:1900-01-01 Published:2010-02-25 Online:2010-02-25

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摘要： 目的评价药物结合技能训练对恢复期精神分裂症患者生活质量和社会功能的影响。方法80例恢复期精神分裂症患者经病例配对分为2个组，每组各40例。研究组使用抗精神病药物联合技能训练，对照组单纯使用抗精神病药物，共观察12个月。在治疗前、治疗结束时分别进行阳性和阴性症状评定量表(PANSS)、生活质量综合评定问卷(GQOLI-74)和社会功能缺陷筛选表(SDSS)评定。结果治疗12个月后，两组PANSS总分及各因子分均较治疗前下降(P<0.05～0.01)，两组间的减分有非常显著性差异(P<0.01)；研究组在生活质量(物质生活因子除外)和社会功能各个方面的改善好于对照组(P<0.05～0.01)。结论在药物治疗同时结合技能训练有助于恢复期精神分裂症患者精神症状缓解，生活质量和社会功能改善，促进康复。

关键词: 精神分裂症, 技能训练, 生活质量, 社会功能

Abstract: ObjectiveTo explore the influence of antipsychotics combined with skill traning on quality of life and social function of patients with schizophrenia at recovery.Methods80 patients with schizophrenia were randomly divided into study group (n=40, antipsychotics plus skill training)and control group (n﹦40, only antipsychotics) for 1-year treatment. At pre-treatment and end of treatment, both groups were assessed with Positiveand and Negative Symptom Scale (PANSS), Generic Quality Of Life Inventory-74 (GQOLI-74) and Social Disability Screening Schedue(SDSS) respectively to evaluate their effects, quality of life and social funtion.ResultsAfter 1-year treatment, the general scores of PANSS and each factors in both groups decreased significantly compared with the baseline(P<0.05～0.01), and the significant difference was found between two groups(P<0.01). Improvement of each factor score of FAD(except factor of the material life) and SDSS in study group were more better than those in control group(P<0.05～0.01).ConclusionTreatment with antipsychotics plus skill traning is helpful to release the mental syndrome, improve quality of life and social funtion, and facilitate the recovery of the patients with schizophrenia at recovery.

Key words: schizophrenia, skill training, quality of life, social function