《中国康复理论与实践》

《中国康复理论与实践》 ›› 2011, Vol. 17 ›› Issue (10): 993-996.

• 论文 • 上一篇    下一篇

脑卒中住院康复患者尿路感染病原菌的分布及其耐药性

孟祥博，刘元标，陈丽娜，方翔   

  1. 杭州市第一人民医院，a：康复医学科；b：检验科，浙江杭州市310006。
  • 收稿日期:2011-07-14 修回日期:2011-08-17 出版日期:2011-10-25 发布日期:2011-10-25

Distribution and Antibiotic Resistance of Pathogens from Urinary Tract Infection among Stroke Inpatients for Rehabilitation

MENG Xiang-bo, LIU Yuan-biao, CHEN Li-na, et al.   

  1. Department of Rehabilitation Medicine, Hangzhou First People's Hospital, Hangzhou310006, Zhejiang, China
  • Received:2011-07-14 Revised:2011-08-17 Published:2011-10-25 Online:2011-10-25

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摘要： 目的了解脑卒中住院康复患者尿路感染病原菌的分布及其耐药情况。方法收集2009 年3 月~2011 年3 月本科脑卒中住院康复患者尿路感染病原学资料，并采用WHONET 耐药分析软件对结果进行统计分析。结果洁尿标本分离出203 株病原菌，主要分别为大肠埃希氏菌72 株(35.5%)、肠球菌属55 株(27.1%)、肺炎克雷伯氏菌18 株(8.9%)和真菌22 株(10.8%)。主要革兰阴性杆菌对氨苄西林、左氧氟沙星、头孢噻肟的耐药率较高；大肠埃希氏菌产超广谱β内酰胺酶(ESBLs)占38.9%，肺炎克雷伯氏菌产ESBLs 占44.4%。肠球菌属对大多数常用抗菌药物表现出较高度耐药。真菌对药物敏感性很高。结论革兰阴性菌是脑卒中住院康复患者尿路感染的主要病原菌；耐药菌株特别是多重耐药菌株增加较快。

关键词: 尿路感染, 病原菌, 耐药性, 脑卒中, 康复

Abstract: Objective To investigate the bacterial distribution and antibiotic resistance situation of urinary tract infection (UTI) among the inpatients following stroke. Methods The clinical data of pathogens from UTI in the stroke patients in our hospital from March 2009 to March 2011 were collected and analyzed with WHONET software. Results Among 203 strains from UTI, the most common pathogens were Escherichia coli (35.5%), Enterococcus (27.1%), Klebsiella (8.9%) and Fungi (10.8%). The main Gram negative bacilli were found highly resistant to ampicillin, levofloxacin and cefotaxim. 38.9% of Escherichia coli and 44.4% of Klebsiella produced extended-spectrum β-lactamases (ESBLs) respectively. The rate of antibiotic resistance of Enterococcus was high to the most of antibiotics commonly used. The fungi were highly sensitive to the drugs. Conclusion Gram negative bacilli are the main pathogens of urinary tract infection in stroke inpatients. Drug resistant strains, especially those with severe multiple resistance, increase fast.

Key words: urinary tract infection, pathogens, antibiotic resistance, stroke, rehabilitation